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| Ingredient | ATC Level 1 | ATC Level 2 | Year Of Switch | Country | Status | Additional Information |
|---|---|---|---|---|---|---|
| Haloprogin (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | — | Canada | N.R. | Not registered or not marketed. |
| Isoconazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | — | Canada | N.R. | Not registered or not marketed. |
| Ketoconazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1994 | Canada | OTC | — |
| Miconazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1994 | Canada | OTC | — |
| Miconazole & Hydrocortisone (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | — | Canada | N.R. | Not registered or not marketed. |
| Naftifine (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | — | Canada | N.R. | Not registered or not marketed. |
| Natamycin (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | — | Canada | N.R. | Not registered or not marketed. |
| Neticonazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | — | Canada | N.R. | Not registered or not marketed. |
| Nystatin | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1998 | Canada | OTC | For topical use on the skin. |
| Oxiconazole | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1997 | Canada | OTC | Switched directly to OTC status in 1997, but no product currently marketed (discontinued since 2002). |
| Selenium sulphide | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2003 | Canada | OTC | — |
| Sulconazole nitrate (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | — | Canada | N.R. | Not registered or not marketed. |
| Terbinafine | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | — | Canada | Rx | — |
| Tioconazole | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1995 | Canada | OTC | No OTC product currently marketed (discontinued since 2002). |
| Tolnaftate | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | — | Canada | OTC | — |
| Hyaluronic acid (topical) | D Dermatologicals. Dermatologicals | D03. Preparations for treatment of wounds and ulcers | 1998 | Canada | OTC | — |
| Calcipotriol | D Dermatologicals. Dermatologicals | D05. Antipsoriatics | — | Canada | Rx | — |
| Aciclovir (topical) | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | Canada | Rx | Spelt Acyclovir. |
| Chlortetracycline (topical) | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | Canada | Rx | — |
| Docosanol (topical) | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | 2002 | Canada | OTC | On 22 September 2002, the Nonprescription Drug Scheduling Advisory Committee agreed to support unscheduled (general sale) status for docosanol cream 10% if the products labelling and package insert could be amended to show that the maximum duration of treatment was 10 days. |
| Famciclovir | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | Canada | Rx | — |
| Idoxuridine (topical) | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | Canada | N.R. | Not registered or not marketed. |
| Lysozyme HCl | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | Canada | N.R. | Not registered or not marketed. |
| Mupirocin (topical) | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | 1999 | Canada | OTC | — |
| Penciclovir (topical) | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | Canada | N.R. | Not registered or not marketed (discontinued since 2009). |
| Podofilox (Podophyllotoxin) | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | Canada | N.R. | Not registered or not marketed. |
| Silver sulphadiazine 1% | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | Canada | N.R. | Not registered or not marketed (discontinued since 2002). |
| Tetracycline | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | Canada | Rx | — |
| Alclometasone (topical) | D Dermatologicals. Dermatologicals | D07. Corticosteroids, dermatological preparations | — | Canada | N.R. | Not registered or not marketed. |
| Clobetasone butyrate (topical) | D Dermatologicals. Dermatologicals | D07. Corticosteroids, dermatological preparations | 2006 | Canada | OTC | OTC up to 0.05% concentration in cream preparations for topical use on the skin. |
| Hydrocortisone (topical) | D Dermatologicals. Dermatologicals | D07. Corticosteroids, dermatological preparations | 1986 | Canada | OTC | 0.5% topical switched in 1986, 1% topical switched in 2014. |
| Prednisolone | D Dermatologicals. Dermatologicals | D07. Corticosteroids, dermatological preparations | — | Canada | Rx | — |
| Triamcinolone | D Dermatologicals. Dermatologicals | D07. Corticosteroids, dermatological preparations | 2015 | Canada | OTC | Topical use (ATC code D07): concentration of maximum 1% (as single medical ingredient or in combination). Nasal spray (ATC code R01): 55 microgram per spray for those 12 years of age and older. |
| Benzalkonium chloride | D Dermatologicals. Dermatologicals | D08. Antiseptics and disinfectants | — | Canada | OTC | — |
| Povidone iodine | D Dermatologicals. Dermatologicals | D08. Antiseptics and disinfectants | — | Canada | N.R. | Not registered or not marketed. |
| Triclosan | D Dermatologicals. Dermatologicals | D08. Antiseptics and disinfectants | — | Canada | OTC | Being phased out in Canada under the CEPA 1999 Chemicals Management Plan. |
| Benzoyl peroxide | D Dermatologicals. Dermatologicals | D10. Anti-acne preparations | 1981 | Canada | OTC | OTC for preparations of 5% or less as a single ingredient. Rx in concentrations greater than 5% or when sold in combination with another medicinal ingredient. |
| Clindamycin | D Dermatologicals. Dermatologicals | D10. Anti-acne preparations | — | Canada | Rx | — |
| Erythromycin (topical) | D Dermatologicals. Dermatologicals | D10. Anti-acne preparations | — | Canada | Rx | — |
| Tretinoin | D Dermatologicals. Dermatologicals | D10. Anti-acne preparations | — | Canada | Rx | Isotretinoin. |
| Minoxidil (topical) | D Dermatologicals. Dermatologicals | D11. Other dermatological preparations | 2000 | Canada | OTC | 2% switched in 2000, 5% switched in 2014. |
| Butoconazole | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G01. Gynecological antiinfectives and antiseptics | — | Canada | Rx | — |
| Clotrimazole (vaginal) | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G01. Gynecological antiinfectives and antiseptics | 1994 | Canada | OTC | Schedule 3 (available without prescription but to be sold from the self-selection area of the pharmacy which is operated under the direct supervision of the pharmacist) for human use in preparations for intra-vaginal use. |
| Miconazole (vaginal) | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G01. Gynecological antiinfectives and antiseptics | 1994 | Canada | OTC | — |
| Propionate Ca+Na (vaginal) | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G01. Gynecological antiinfectives and antiseptics | — | Canada | Rx | — |
| Estriol (vaginal) | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G03. Sex hormones and modulators of the genital system | — | Canada | N.R. | Not registered or not marketed. |
| Levonorgestrel | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G03. Sex hormones and modulators of the genital system | 2005 | Canada | OTC | The 0.75mg two-pill dose was first switched in 2005, the 1.5mg one-pill dose was switched in 2015. |
| Flavoxate hydrochloride | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G04. Urologicals | — | Canada | N.R. | Not registered or not marketed. |
| Phenazopyridine | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G04. Urologicals | — | Canada | Rx | No product currently marketed. |
| Tamsulosin | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G04. Urologicals | — | Canada | Rx | — |