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| Ingredient | ATC Level 1 | ATC Level 2 | Year Of Switch | Country | Status | Additional Information |
|---|---|---|---|---|---|---|
| Haloprogin (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | — | Japan | N.R. | — |
| Isoconazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2008 | Japan | OTC | Cream formulation. 1% in a preparation. Apply 2-3 times a day. |
| Ketoconazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | — | Japan | Rx | — |
| Miconazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1987 | Japan | OTC | Cream, liquid formulation. 1%, once a day. |
| Miconazole & Hydrocortisone (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | — | Japan | N.R. | — |
| Naftifine (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | — | Japan | N.R. | — |
| Natamycin (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | — | Japan | N.R. | — |
| Neticonazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2002 | Japan | OTC | OTC under ATC code D01 and G01. |
| Nystatin | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | — | Japan | OTC | Topical combination drug with chloramphenicol and fradiomycin sulphate. Ointment formulation. 100,000 unit/g in a preparation. Apply several times a day. |
| Oxiconazole | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1993 | Japan | OTC | Liquid and gel formulations. 1% in a preparation. Apply once a day. |
| Oxiconazole | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G01. Gynecological antiinfectives and antiseptics | 2010 | Japan | OTC | Vaginal tablet. 100mg, once a day. |
| Selenium sulphide | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | — | Japan | N.R. | — |
| Sulconazole nitrate (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1993 | Japan | OTC | — |
| Terbinafine | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2002 | Japan | OTC | Cream, liquid formulation. 1%, once a day. |
| Tioconazole | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1991 | Japan | OTC | — |
| Tolnaftate | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | — | Japan | OTC | Ointment, cream, liquid formulation. 2%, apply once or twice a day. |
| Hyaluronic acid (topical) | D Dermatologicals. Dermatologicals | D03. Preparations for treatment of wounds and ulcers | — | Japan | N.R. | — |
| Calcipotriol | D Dermatologicals. Dermatologicals | D05. Antipsoriatics | — | Japan | Rx | — |
| Aciclovir (topical) | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | 2007 | Japan | OTC | Switched in 2007 for recurrent herpes mouth ulcers. Distribution restricted to pharmacies following an initial doctor consultation. 5% cream, ointment formulations. Apply 3-5 times a day. |
| Chlortetracycline (topical) | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | Japan | OTC | 0.5% ointment. Apply several times a day. |
| Docosanol (topical) | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | Japan | N.R. | — |
| Famciclovir | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | Japan | Rx | Not registered or not marketed under this ATC code. Rx under ATC code J05. |
| Idoxuridine (topical) | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | Japan | N.R. | — |
| Lysozyme HCl | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | Japan | OTC | Registration on oral preparations was revoked. Now available as topical combination drugs such as hemorrhoidal preparation. |
| Mupirocin (topical) | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | Japan | Rx | — |
| Penciclovir (topical) | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | Japan | N.R. | — |
| Podofilox (Podophyllotoxin) | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | Japan | N.R. | — |
| Silver sulphadiazine 1% | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | Japan | Rx | — |
| Tetracycline | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | Japan | OTC | Combination of oxytetracycline hydrochloride and hydrocortisone acetate for topical use. Combination of oxytetracycline hydrochloride and polymyxin B for topical use. |
| Alclometasone (topical) | D Dermatologicals. Dermatologicals | D07. Corticosteroids, dermatological preparations | — | Japan | Rx | — |
| Clobetasone butyrate (topical) | D Dermatologicals. Dermatologicals | D07. Corticosteroids, dermatological preparations | — | Japan | Rx | — |
| Hydrocortisone (topical) | D Dermatologicals. Dermatologicals | D07. Corticosteroids, dermatological preparations | 1990 | Japan | OTC | Ointment, cream formulations. 0.05% of Hydrocortisone butyl ester in a preparation. Apply several times a day. |
| Prednisolone | D Dermatologicals. Dermatologicals | D07. Corticosteroids, dermatological preparations | 1992 | Japan | OTC | Ointment, cream formulations. 0.15% of Prednisolone valerate acetate ester in a preparation. Apply several times a day. |
| Triamcinolone | D Dermatologicals. Dermatologicals | D07. Corticosteroids, dermatological preparations | — | Japan | OTC | Rx under ATC code D07. OTC under ATC code A01 since 2006 for the treatment of stomatitis. |
| Benzalkonium chloride | D Dermatologicals. Dermatologicals | D08. Antiseptics and disinfectants | — | Japan | OTC | — |
| Povidone iodine | D Dermatologicals. Dermatologicals | D08. Antiseptics and disinfectants | — | Japan | OTC | — |
| Triclosan | D Dermatologicals. Dermatologicals | D08. Antiseptics and disinfectants | — | Japan | N.R. | — |
| Benzoyl peroxide | D Dermatologicals. Dermatologicals | D10. Anti-acne preparations | — | Japan | Rx | — |
| Clindamycin | D Dermatologicals. Dermatologicals | D10. Anti-acne preparations | — | Japan | Rx | — |
| Erythromycin (topical) | D Dermatologicals. Dermatologicals | D10. Anti-acne preparations | — | Japan | N.R. | — |
| Tretinoin | D Dermatologicals. Dermatologicals | D10. Anti-acne preparations | — | Japan | N.R. | Rx: Trtinoine tocoferil for bedsores. |
| Minoxidil (topical) | D Dermatologicals. Dermatologicals | D11. Other dermatological preparations | 1999 | Japan | OTC | Immediate OTC sale in 1999 (no switch from Rx). 1% liquid formulation for men since 1999. Also 1% for women since 2005. Maximum strength 5% for men since 2009. |
| Butoconazole | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G01. Gynecological antiinfectives and antiseptics | — | Japan | N.R. | — |
| Clotrimazole (vaginal) | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G01. Gynecological antiinfectives and antiseptics | 2011 | Japan | OTC | Vaginal tablet. Daily dose 100mg. 1% cream for external use of vulvar candidiasis, to be used 2-3 times a day in conjunction with vaginal tablets. |
| Miconazole (vaginal) | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G01. Gynecological antiinfectives and antiseptics | 2008 | Japan | OTC | Vaginal tablet. Daily dose 100mg. 1% cream for exrternal use of vulvar candidiasis, 2-3 times a day. |
| Propionate Ca+Na (vaginal) | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G01. Gynecological antiinfectives and antiseptics | — | Japan | N.R. | — |
| Estriol (vaginal) | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G03. Sex hormones and modulators of the genital system | — | Japan | Rx | — |
| Levonorgestrel | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G03. Sex hormones and modulators of the genital system | — | Japan | Rx | — |
| Flavoxate hydrochloride | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G04. Urologicals | 2008 | Japan | OTC | Oral drug for frequent urination. 200mg a dose, 3 times a day. |
| Phenazopyridine | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G04. Urologicals | — | Japan | N.R. | — |