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Ingredient | ATC Level 1 | ATC Level 2 | Year Of Switch | Country | Status | Additional Information |
---|---|---|---|---|---|---|
Estradiol (vaginal) | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G03. Sex hormones and modulators of the genital system | 2022 | UK | OTC | 10 mg vaginal tablets; Treatment of vaginal atrophy due to oestrogen deficiency in postmenopausal women aged 50 years and above, who have not had a period for at least 1 year. |
Tadalafil | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G04. Urologicals | 2023 | UK | OTC | Pharmacy (P) medicine |
Dexibuprofen | M Musculo-skeletal system. Musculo-skeletal system | M01. Antiinflammatory and antirheumatic products | — | UK | Rx | — |
lidocaine / prilocaine | N Nervous system. Nervous system | N01. Anesthetics | — | UK | — | — |
Pholcodine | R Respiratory system. Respiratory system | R05. Cough and cold preparations | — | UK | N.R. | Revocation of all marketing authorisations for Pholcodine medicinal products in the EU due to serious allergic reactions and limited evidence of benefit. Previous status: OTC |
Butamirate citrate | R Respiratory system. Respiratory system | R05. Cough and cold preparations | — | UK | — | No information. |
Atovaquone/Proguanil | P Antiparasitic products, insecticides and repellents. Antiparasitic products, insecticides and repellents | P01. Antiprotozoals | 2017 | UK | OTC | Reclassified to pharmacy only medicine. Tablets for oral use. For prevention of malaria in adults weighing more than 40 kg. Dose: 1 tablet to be taken daily commencing one to two days prior to entering a malaria-endemic area, continuing during the period of stay, continuing for 7 days after leaving the area Maximum dose: 250mg/100mg, Maximum daily dose: 250mg/100mg Maximum pack size: 36 tablets (total number of tablets dispensed dependent on duration of travel with maximum of 93 tablets for 12 weeks’ travel). |
Sildenafil | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G04. Urologicals | 2017 | UK | OTC | Pharmacy only status. For oral use. 50mg film-coated tablets for adult men (18 years and older) with erectile dysfunction. Maximum dose 50mg, maximum daily dose 50mg, maximum pack size 8 tablets. |
Aciclovir (systemic use) | J Antiinfectives for systemic use. Antiinfectives for systemic use | J05. Antivirals for systemic use | — | UK | Rx | — |
Adapalene | D Dermatologicals. Dermatologicals | D10. Anti-acne preparations | — | UK | Rx | — |
Dexketoprofen | M Musculo-skeletal system. Musculo-skeletal system | M01. Antiinflammatory and antirheumatic products | — | UK | Rx | — |
Valaciclovir | J Antiinfectives for systemic use. Antiinfectives for systemic use | J05. Antivirals for systemic use | — | UK | Rx | — |
Econazole (vaginal) | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G01. Gynecological antiinfectives and antiseptics | 1992 | UK | OTC | Pharmacy only status when for external use only for the treatment of vaginal candidiasis. |
Fusafungine | R Respiratory system. Respiratory system | R02. Throat preparations | — | UK | Rx | — |
Ulipristal acetate | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G03. Sex hormones and modulators of the genital system | 2015 | UK | OTC | Ulipristal acetate 30mg was switched to non-prescription status via the centralised procedure in the entire European Union through a European Commission Decision dated 7 January 2015. It is indicated for emergency contraception within 120 hours (5 days) of unprotected sexual intercourse or contraceptive failure. |
Oxitriptan | N Nervous system. Nervous system | N06. Psychoanaleptics | — | UK | N.R. | Not registered or not marketed. |
Yohimbine | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G04. Urologicals | — | UK | Rx | — |
Cetrimide | D Dermatologicals. Dermatologicals | D08. Antiseptics and disinfectants | — | UK | OTC | External use only. General Sale. |
Azelaic acid | D Dermatologicals. Dermatologicals | D10. Anti-acne preparations | — | UK | Rx | — |
Diosmin | C Cardiovascular system. Cardiovascular system | C05. Vasoprotectives | — | UK | N.R. | Not registered or not marketed. |
Metronidazole | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | UK | Rx | — |
Desloratadine | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | — | UK | Rx | — |
Antazoline | S Sensory organs. Sensory organs | S01. Ophthalmologicals | — | UK | OTC | Pharmacy-only in combination: Xylometazoline 0.05% w/v Antazoline 0.5% w/v. For the temporary relief of redness and itching of the eye due to seasonal and perennial allergies such as hay fever or house dust allergy. |
Neomycin sulfate | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | UK | Rx | — |
Diosmectite | A Alimentary tract and metabolism. Alimentary tract and metabolism | A07. Antidiarrheals, intestinal antiinflammatory/antiinfective agents | — | UK | N.R. | Not registered or not marketed. |
Alverine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A03. Drugs for functional gastrointestinal disorders | — | UK | OTC | 60mg alverine citrate for the relief of smooth muscle spasm, in conditions such as irritable bowel syndrome, painful diverticular disease of the colon and primary dysmenorrhoea. Pharmacy-only status. |
Chlorhexidine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A01. Stomatological preparations | — | UK | OTC | General sale. |
Chloroxylenol | D Dermatologicals. Dermatologicals | D08. Antiseptics and disinfectants | — | UK | OTC | General Sales. Maximum strength for internal use 0.5%. Maximum strength for external use 5%. |
Isoconazole (vaginal) | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G01. Gynecological antiinfectives and antiseptics | — | UK | OTC | Pharmacy supply only in external use for the treatment of vaginal candidiasis. |
Esomeprazole | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | 2013 | UK | OTC | Esomeprazole 20mg was switched to non-prescription status under the centralised procedure in the entire European Union through a European Commission Decision dated 26 August 2013. It is indicated for the short-term treatment of reflux symptoms (e.g. heartburn and acid regurgitation) in adults. Recommended daily dose: one 20mg gastroresistant tablet. Maximum duration of treatment: 2 weeks. Reclassified from pharmacy to general sale (GSL) in January 2015. |
Trimethoprim | J Antiinfectives for systemic use. Antiinfectives for systemic use | J01. Antibacterials for systemic use | — | UK | Rx | — |
Oxybutynin | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G04. Urologicals | — | UK | Rx | — |
Lodoxamide | S Sensory organs. Sensory organs | S01. Ophthalmologicals | — | UK | OTC | Pharmacy-only status. For the treatment of ocular signs and symptoms of allergic conjunctivitis, in adults and in children aged 4 years and over. Maximum strength: equivalent to 0.1% lodoxamide. |
Guaifenesin | R Respiratory system. Respiratory system | R05. Cough and cold preparations | — | UK | OTC | General sales up to 200mg. Also OTC in combinations = "guaifenesin + paracetamol + phenylephrine", "guaifenesin + paracetamol + phenylephrine + cetylpyridinium chloride", "guaifenesin + cetylpyridinium chloride", "guaifenesin + pseudoephedrine", "guaifenesin + cetylpyridinium chloride + purified honey + sucrose", "guaifenesin + levomenthol", "guaifenesin + pseudoephedrine + triprolidine". |
Erdosteine | R Respiratory system. Respiratory system | R05. Cough and cold preparations | — | UK | Rx | — |
Racecadotril | A Alimentary tract and metabolism. Alimentary tract and metabolism | A07. Antidiarrheals, intestinal antiinflammatory/antiinfective agents | — | UK | Rx | — |
Strontium chloride (toothpaste) | Non-classified -. - | n. a. | — | UK | OTC | Strontium chloride hexahydrate. General sale for dental use. |
Potassium nitrate (toothpaste) | Non-classified -. - | n. a. | — | UK | OTC | Maximum dose for general sale is 100mg. |
Decaline | Non-classified -. - | n. a. | — | UK | N.R. | Not registered or not marketed. |
Bronopol | Non-classified -. - | n. a. | — | UK | N.R. | Not registered or not marketed. |
Polymyxin B (topical) | S Sensory organs. Sensory organs | S03. Ophthalmological and otological preparations | — | UK | Rx | — |
Chloramphenicol | S Sensory organs. Sensory organs | S03. Ophthalmological and otological preparations | 2005 | UK | OTC | Chloramphenicol 0.5% eye drops were switched to pharmacy-only (P) status in June 2005, in a pack size of not more than 10ml. The product, a broad spectrum antibiotic active against a wide range of bacteria, can be used for the treatment of acute bacterial conjunctivitis in children aged 2 years and over, adults and the elderly. The approved dosage is 1 drop every 2 hours for the first 48 hours and 4 hourly thereafter. The course of treatment is 5 days. Chloramphenicol eye ointment 1% switched to Pharmacy status in 2007 for the treatment of acute bacterial conjunctivitis. |
Sulfacetamide (topical) | S Sensory organs. Sensory organs | S01. Ophthalmologicals | — | UK | N.R. | Not registered or not marketed. |
Trip(r)olidine | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | — | UK | OTC | Pharmacy only supply. |
Tripelennamine | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | — | UK | N.R. | Not registered or not marketed. |
Promethazine | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | — | UK | OTC | Pharmacy only supply. |
Oxatomide | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | — | UK | N.R. | Not registered or not marketed. |
Mequitazine | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | — | UK | N.R. | Not registered or not marketed. |
Mepyramine maleate | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | — | UK | OTC | For topical use. General sale if maximum strength = 2% and if sold for symptomatic relief of insect stings and bites and nettle stings, in adults and children aged 2 years and over. A spray formulation containing 1% benzocaine and 0.5% mepyramine maleate may be supplied on general sale for the treatment of insect bites and stings, nettle stings and jellyfish stings in adults and children aged 2 years and over. Maximum pack size 30ml. |
Meclozine | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | — | UK | OTC | Pharmacy only supply. |
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