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| Ingredient | ATC Level 1 | ATC Level 2 | Year Of Switch | Country | Status | Additional Information |
|---|---|---|---|---|---|---|
| Hexetidine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A01. Stomatological preparations | — | Germany | OTC | — |
| Fluoride (sodium) | A Alimentary tract and metabolism. Alimentary tract and metabolism | A01. Stomatological preparations | 1986 | Germany | OTC | Maximum daily dose of 2mg is OTC. Gel for topical use in dentistry is OTC. Packs up to 25g. For adults and children over 6 years. Maximum dose of 7mg of fluoride to be applied once a week. |
| Chlorhexidine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A01. Stomatological preparations | — | Germany | OTC | Also OTC under ATC code D08. |
| Pantoprazole | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | 2009 | Germany | OTC | Pantoprazole 20mg was switched to non-prescription status in the entire European Union through a Decision of the European Commission under the centralised procedure dated 12 June 2009. |
| Sucralfate | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | — | Germany | Rx | — |
| Rabeprazole | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | — | Germany | Rx | — |
| Aluminium hydroxide | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | — | Germany | OTC | — |
| Cetraxate | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | — | Germany | N.R. | Not registered or not marketed. |
| Ranitidine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | 1999 | Germany | OTC | Oral use, dosage up to 75mg. For heartburn and reflux, with a maximum duration of two weeks. |
| Omeprazole | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | 2009 | Germany | OTC | Omeprazole 20mg oral formulations for the treatment of heartburn and gastric reflux. Maximum daily dose 20mg, maximum pack size 14 doses, maximum duration of treatment 14 days. |
| Esomeprazole | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | 2013 | Germany | OTC | Esomeprazole 20mg was switched to non-prescription status under the centralised procedure in the entire European Union through a European Commission Decision dated 26 August 2013. It is indicated for the short-term treatment of reflux symptoms (e.g. heartburn and acid regurgitation) in adults. Recommended daily dose: one 20mg gastroresistant tablet. Maximum duration of treatment: 2 weeks. |
| Lansoprazole | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | — | Germany | Rx | — |
| Cimetidine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | — | Germany | Rx | — |
| Famotidine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | 1999 | Germany | OTC | Dosage 10mg. For the short-term treatment of heartburn and reflux in adults and children over 16 years, with a maximum duration of two weeks. |
| Carbenoxolone | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | — | Germany | Rx | — |
| Nizatidine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | — | Germany | Rx | — |
| Calcium carbonate | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | — | Germany | OTC | — |
| Propantheline | A Alimentary tract and metabolism. Alimentary tract and metabolism | A03. Drugs for functional gastrointestinal disorders | — | Germany | Rx | Propantheline bromide. |
| Mebeverine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A03. Drugs for functional gastrointestinal disorders | — | Germany | Rx | — |
| Alverine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A03. Drugs for functional gastrointestinal disorders | — | Germany | N.R. | Not registered or not marketed. |
| Dimeticone | A Alimentary tract and metabolism. Alimentary tract and metabolism | A03. Drugs for functional gastrointestinal disorders | — | Germany | OTC | — |
| Metoclopramide | A Alimentary tract and metabolism. Alimentary tract and metabolism | A03. Drugs for functional gastrointestinal disorders | — | Germany | Rx | — |
| Dicyclomine (Dicycloverine) | A Alimentary tract and metabolism. Alimentary tract and metabolism | A03. Drugs for functional gastrointestinal disorders | — | Germany | N.R. | Not registered or not marketed. |
| Hyoscine butylbromide | A Alimentary tract and metabolism. Alimentary tract and metabolism | A03. Drugs for functional gastrointestinal disorders | 1966 | Germany | OTC | — |
| Domperidone | A Alimentary tract and metabolism. Alimentary tract and metabolism | A03. Drugs for functional gastrointestinal disorders | — | Germany | Rx | — |
| Hyoscine (Scopolamine) | A Alimentary tract and metabolism. Alimentary tract and metabolism | A04. Antiemetics and antinauseants | — | Germany | Rx | — |
| Dimenhydrinate (diphenhydramine and 8-chlorotheophylline) | A Alimentary tract and metabolism. Alimentary tract and metabolism | A04. Antiemetics and antinauseants | — | Germany | OTC | — |
| Hymecromone | A Alimentary tract and metabolism. Alimentary tract and metabolism | A05. Bile and liver therapy | — | Germany | OTC | — |
| Picosulfate (sodium) | A Alimentary tract and metabolism. Alimentary tract and metabolism | A06. Laxatives | — | Germany | OTC | — |
| Macrogol (Polyethylene glycol 3350) | A Alimentary tract and metabolism. Alimentary tract and metabolism | A06. Laxatives | — | Germany | OTC | — |
| Lactulose | A Alimentary tract and metabolism. Alimentary tract and metabolism | A06. Laxatives | — | Germany | OTC | — |
| Lactitol | A Alimentary tract and metabolism. Alimentary tract and metabolism | A06. Laxatives | 1995 | Germany | OTC | — |
| Bisacodyl | A Alimentary tract and metabolism. Alimentary tract and metabolism | A06. Laxatives | — | Germany | OTC | — |
| Diosmectite | A Alimentary tract and metabolism. Alimentary tract and metabolism | A07. Antidiarrheals, intestinal antiinflammatory/antiinfective agents | — | Germany | OTC | — |
| Racecadotril | A Alimentary tract and metabolism. Alimentary tract and metabolism | A07. Antidiarrheals, intestinal antiinflammatory/antiinfective agents | 2013 | Germany | OTC | Solid dosage forms. For the treatment of acute diarrhoea, maximum duration of treatment 3 days. Adults (over 18 years): 100mg per dosage form, maximum pack size 1,000mg. Children aged 12 years and older: Racecadotril 30mg per single dose in combination with oral re-hydration, maximum pack size 450mg. |
| Nifuroxazide | A Alimentary tract and metabolism. Alimentary tract and metabolism | A07. Antidiarrheals, intestinal antiinflammatory/antiinfective agents | — | Germany | N.R. | Not registered or not marketed. |
| Loperamide | A Alimentary tract and metabolism. Alimentary tract and metabolism | A07. Antidiarrheals, intestinal antiinflammatory/antiinfective agents | 1993 | Germany | OTC | Maximum daily dose for OTC use 12mg, restricted to treatment of acute diarrhoea. Maximum pack size 24mg. Without prescription only for adults and children over 12 years. |
| Orlistat | A Alimentary tract and metabolism. Alimentary tract and metabolism | A08. Antiobesity preparations | 2009 | Germany | OTC | Orlistat 60 mg was switched to non-prescription status under the centralised procedure in the entire European Union through a European Commission Decision dated 12 January 2009. The switch was also implemented in Croatia, Norway and Switzerland. |
| Vitamin A (Retinol) | A Alimentary tract and metabolism. Alimentary tract and metabolism | A11. Vitamins | — | Germany | OTC | Maximum dose for OTC status is 50 000 I.U. |
| Selenium | A Alimentary tract and metabolism. Alimentary tract and metabolism | A12. Mineral supplements | 1993 | Germany | OTC | Maximum dose for OTC status is 70 micrograms. |
| Tranexamic acid | B Blood and blood forming organs. Blood and blood forming organs | B02. Antihemorrhagics | — | Germany | Rx | — |
| Nitro-glycerine | C Cardiovascular system. Cardiovascular system | C01. Cardiac therapy | — | Germany | Rx | — |
| Ubidecarenone | C Cardiovascular system. Cardiovascular system | C01. Cardiac therapy | — | Germany | OTC | Only registered as homeopathic medicine. |
| Adenosine | C Cardiovascular system. Cardiovascular system | C01. Cardiac therapy | — | Germany | Rx | — |
| Diosmin | C Cardiovascular system. Cardiovascular system | C05. Vasoprotectives | — | Germany | N.R. | Not registered or not marketed. |
| Simvastatin | C Cardiovascular system. Cardiovascular system | C10. Lipid modifying agents | — | Germany | Rx | — |
| Lovastatin | C Cardiovascular system. Cardiovascular system | C10. Lipid modifying agents | — | Germany | Rx | — |
| Natamycin (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1978 | Germany | OTC | External use. |
| Butenafine | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | — | Germany | N.R. | Not registered or not marketed. |
| Bifonazole | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1988 | Germany | OTC | — |
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