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| Ingredient | ATC Level 1 | ATC Level 2 | Year Of Switch | Country | Status | Additional Information |
|---|---|---|---|---|---|---|
| Minoxidil (topical) | D Dermatologicals. Dermatologicals | D11. Other dermatological preparations | — | Italy | OTC | SOP (behind the counter). External use 2% and 5%, 60ml. |
| Levonorgestrel | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G03. Sex hormones and modulators of the genital system | 2016 | Italy | OTC | Levonorgestrel 1 TABLET, 1,5 mg was switched to non-prescription status via the centralised procedure. SOP (behnid the counter) status, but a prescription is necessary for girls under 18 years of age. |
| Hyaluronic acid (topical) | D Dermatologicals. Dermatologicals | D03. Preparations for treatment of wounds and ulcers | — | Italy | OTC | Also OTC under ATC code S01. |
| Benzoyl peroxide | D Dermatologicals. Dermatologicals | D10. Anti-acne preparations | — | Italy | OTC | — |
| Clotrimazole (vaginal) | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G01. Gynecological antiinfectives and antiseptics | 2007 | Italy | OTC | Vaginal cream (2%) and tablets (100mg). |
| Miconazole (vaginal) | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G01. Gynecological antiinfectives and antiseptics | 2012 | Italy | OTC | SOP (behind the counter). |
| Fenticonazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | — | Italy | OTC | Dosage of 2% or 200mg. Without prescription - SOP (advertising not allowed). Also SOP under ATC code G01. |
| Tioconazole | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | — | Italy | OTC | — |
| Nicotine (gum) | N Nervous system. Nervous system | N07. Other nervous system drugs | — | Italy | OTC | — |
| Benzalkonium chloride | D Dermatologicals. Dermatologicals | D08. Antiseptics and disinfectants | — | Italy | OTC | Alone and in combination. Also OTC under ATC code S01. |
| Terbinafine | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2008 | Italy | OTC | — |
| Omeprazole | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | 2011 | Italy | OTC | Omeprazole 20mg for the treatment of reflux symptoms (e.g. heartburn, acid regurgitation) in adults, once daily for 14 days. Pack sizes 7 or 14 tablets. |
| Pantoprazole | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | 2009 | Italy | OTC | Pantoprazole 20mg was switched to non-prescription status in the entire European Union through a Decision of the European Commission under the centralised procedure dated 12 June 2009. |
| Calcium carbonate | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | — | Italy | OTC | OTC only in combination. |
| Ranitidine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | 2010 | Italy | OTC | 75mg tablets. |
| Fluoride (sodium) | A Alimentary tract and metabolism. Alimentary tract and metabolism | A01. Stomatological preparations | — | Italy | OTC | — |
| Isoconazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2012 | Italy | OTC | Without prescription - SOP (advertising not allowed). |
| Miconazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2012 | Italy | OTC | Also without prescription - SOP (advertising not allowed) under ATC code A01. |
| Naftifine (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2012 | Italy | OTC | Dosage 1%, 30g - 30ml. SOP (advertising not allowed). |
| Penciclovir (topical) | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | 2008 | Italy | OTC | External use. |
| Silver sulphadiazine 1% | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | 2012 | Italy | OTC | Without prescription - SOP (advertising not allowed). Also SOP under ATC code D03. |
| Hydrocortisone (topical) | D Dermatologicals. Dermatologicals | D07. Corticosteroids, dermatological preparations | 1983 | Italy | OTC | Also OTC under ATC code C05 (in combination). |
| Povidone iodine | D Dermatologicals. Dermatologicals | D08. Antiseptics and disinfectants | — | Italy | OTC | Also OTC (advertising allowed) under ATC codes G01 and R02. |
| Dimenhydrinate (diphenhydramine and 8-chlorotheophylline) | A Alimentary tract and metabolism. Alimentary tract and metabolism | A04. Antiemetics and antinauseants | — | Italy | OTC | — |
| Hyoscine (Scopolamine) | A Alimentary tract and metabolism. Alimentary tract and metabolism | A04. Antiemetics and antinauseants | — | Italy | OTC | Not registered or not marketed for ATC04. OTC for ATC A03 - anticholinergic. |
| Hymecromone | A Alimentary tract and metabolism. Alimentary tract and metabolism | A05. Bile and liver therapy | — | Italy | OTC | Without prescription (public advertising not allowed). |
| Bisacodyl | A Alimentary tract and metabolism. Alimentary tract and metabolism | A06. Laxatives | — | Italy | OTC | — |
| Lactitol | A Alimentary tract and metabolism. Alimentary tract and metabolism | A06. Laxatives | — | Italy | OTC | — |
| Lactulose | A Alimentary tract and metabolism. Alimentary tract and metabolism | A06. Laxatives | — | Italy | OTC | — |
| Macrogol (Polyethylene glycol 3350) | A Alimentary tract and metabolism. Alimentary tract and metabolism | A06. Laxatives | 2010 | Italy | OTC | SOP (advertising not allowed). Dosage 5.9g powder only for adults. |
| Picosulfate (sodium) | A Alimentary tract and metabolism. Alimentary tract and metabolism | A06. Laxatives | — | Italy | OTC | — |
| Loperamide | A Alimentary tract and metabolism. Alimentary tract and metabolism | A07. Antidiarrheals, intestinal antiinflammatory/antiinfective agents | 1998 | Italy | OTC | — |
| Sucralfate | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | — | Italy | OTC | Rx under ATC code A02. OTC under ATC code M01, in combination with ketoprofen. |
| Orlistat | A Alimentary tract and metabolism. Alimentary tract and metabolism | A08. Antiobesity preparations | 2009 | Italy | OTC | Orlistat 60 mg was switched to non-prescription status under the centralised procedure in the entire European Union through a European Commission Decision dated 12 January 2009. The switch was also implemented in Croatia, Norway and Switzerland. Orlistat 60mg has SOP (non-advertisable) status in Italy. |
| Cimetidine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | 1993 | Italy | OTC | Authorised with a maximum dose of 200mg. |
| Clobetasone butyrate (topical) | D Dermatologicals. Dermatologicals | D07. Corticosteroids, dermatological preparations | 2013 | Italy | OTC | — |
| Dimeticone | A Alimentary tract and metabolism. Alimentary tract and metabolism | A03. Drugs for functional gastrointestinal disorders | — | Italy | OTC | In combination. OTC under ATC codes A02 and A07 (in combination with activated carbon). |
| Ketoconazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2007 | Italy | OTC | — |
| Hexetidine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A01. Stomatological preparations | — | Italy | OTC | — |
| Ubidecarenone | C Cardiovascular system. Cardiovascular system | C01. Cardiac therapy | — | Italy | OTC | Dosage 50mg. SOP (advertising not allowed). |
| Hyoscine butylbromide | A Alimentary tract and metabolism. Alimentary tract and metabolism | A03. Drugs for functional gastrointestinal disorders | 1998 | Italy | OTC | — |
| Aciclovir (topical) | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | 2007 | Italy | OTC | Aciclovir 5% - 2g and 3g. |
| Amorolfine (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2012 | Italy | OTC | — |
| Bifonazole | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | — | Italy | OTC | Topical form with 1% concentration. |
| Metoclopramide | A Alimentary tract and metabolism. Alimentary tract and metabolism | A03. Drugs for functional gastrointestinal disorders | — | Italy | OTC | Dosage 5mg. |
| Ciclopirox Olamine | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2012 | Italy | OTC | OTC (advertising allowed) as nail polish. Other topical formulations with a dosage of 1% are classified as SOP (advertising not allowed). Also SOP under ATC code G01 as vaginal cream, suppositories or lather. |
| Clotrimazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2007 | Italy | OTC | Dosage 1%. |
| Nicotine (patch) | N Nervous system. Nervous system | N07. Other nervous system drugs | 1993 | Italy | OTC | — |
| Econazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2007 | Italy | OTC | Without prescription - SOP (advertising not allowed). |
| Benzydamine | M Musculo-skeletal system. Musculo-skeletal system | M01. Antiinflammatory and antirheumatic products | — | Italy | OTC | Not registered or not marketed under ATC code M01. OTC (advertising allowed) under ATC codes A01 (in combination with cetylpyridinium chloride), G02 and R02. Without prescription - SOP (advertising not allowed) under ATC code M02. |
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