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Ingredient ATC Level 1 ATC Level 2 Year Of Switch Country Status Additional Information
Miconazole (vaginal) G Genito urinary system and sex hormones. Genito urinary system and sex hormones G01. Gynecological antiinfectives and antiseptics 1994 Canada OTC —
Diclofenac (topical) M Musculo-skeletal system. Musculo-skeletal system M02. Topical products for joint and muscular pain 2008 Canada OTC 1% topical switched in 2008, 2% topical switched in 2014. Schedule 3 (available without prescription but to be sold from the self-selection area of the pharmacy which is operated under the direct supervision of the pharmacist) when sold as a single medicinal ingredient for topical use on the skin for not more than 7 days, in concentrations greater than 1.16% and less than or equal to 2.32% - in package sizes containing no more than 2.6g of diclofenac diethylamine. General sale when sold as a single medicinal ingredient for topical use on the skin in concentrations of not more than 1.16% for not more than 7 days.
Triamcinolone D Dermatologicals. Dermatologicals D07. Corticosteroids, dermatological preparations 2015 Canada OTC Topical use (ATC code D07): concentration of maximum 1% (as single medical ingredient or in combination). Nasal spray (ATC code R01): 55 microgram per spray for those 12 years of age and older.
Clotrimazole (vaginal) G Genito urinary system and sex hormones. Genito urinary system and sex hormones G01. Gynecological antiinfectives and antiseptics 1994 Canada OTC Schedule 3 (available without prescription but to be sold from the self-selection area of the pharmacy which is operated under the direct supervision of the pharmacist) for human use in preparations for intra-vaginal use.
Levonorgestrel G Genito urinary system and sex hormones. Genito urinary system and sex hormones G03. Sex hormones and modulators of the genital system 2005 Canada OTC The 0.75mg two-pill dose was first switched in 2005, the 1.5mg one-pill dose was switched in 2015.
Bufexamac (topical) M Musculo-skeletal system. Musculo-skeletal system M01. Antiinflammatory and antirheumatic products 1998 Canada OTC Schedule 2 (a prescription is not required but the medicine is only available from the pharmacist, no public access and no self-selection).
Docosanol (topical) D Dermatologicals. Dermatologicals D06. Antibiotics and chemotherapeutics for dermatological use 2002 Canada OTC On 22 September 2002, the Nonprescription Drug Scheduling Advisory Committee agreed to support unscheduled (general sale) status for docosanol cream 10% if the products labelling and package insert could be amended to show that the maximum duration of treatment was 10 days.
Hydrocortisone (topical) D Dermatologicals. Dermatologicals D07. Corticosteroids, dermatological preparations 1986 Canada OTC 0.5% topical switched in 1986, 1% topical switched in 2014.
Triclosan D Dermatologicals. Dermatologicals D08. Antiseptics and disinfectants — Canada OTC Being phased out in Canada under the CEPA 1999 Chemicals Management Plan.
Minoxidil (topical) D Dermatologicals. Dermatologicals D11. Other dermatological preparations 2000 Canada OTC 2% switched in 2000, 5% switched in 2014.
Nicotine (nasal spray) N Nervous system. Nervous system N07. Other nervous system drugs 2003 Canada OTC —
Fluoride (sodium) A Alimentary tract and metabolism. Alimentary tract and metabolism A01. Stomatological preparations 1998 Canada OTC Regulated as a natural health product.
Omeprazole A Alimentary tract and metabolism. Alimentary tract and metabolism A02. Drugs for acid related disorders 2014 Canada OTC OTC when indicated for a 14-day treatment of frequent heartburn at a daily dose of 20mg.
Methenamine J Antiinfectives for systemic use. Antiinfectives for systemic use J01. Antibacterials for systemic use 1998 Canada OTC Ethical OTC status (medicine which does not require a prescription but is generally prescribed by a medical practitioner).
Tolnaftate D Dermatologicals. Dermatologicals D01. Antifungals for dermatological use — Canada OTC —
Famotidine A Alimentary tract and metabolism. Alimentary tract and metabolism A02. Drugs for acid related disorders 1996 Canada OTC For the treatment & prevention of acid-related gastrointestinal symptoms in adults and children over 12 years of age. Dosage is 10mg per tablet, Maximum Daily Dose is 20mg (treatment should not exceed two weeks). 20 & 40mg dosages switched in 2007.
Mupirocin (topical) D Dermatologicals. Dermatologicals D06. Antibiotics and chemotherapeutics for dermatological use 1999 Canada OTC —
Clobetasone butyrate (topical) D Dermatologicals. Dermatologicals D07. Corticosteroids, dermatological preparations 2006 Canada OTC OTC up to 0.05% concentration in cream preparations for topical use on the skin.
Oxiconazole D Dermatologicals. Dermatologicals D01. Antifungals for dermatological use 1997 Canada OTC Switched directly to OTC status in 1997, but no product currently marketed (discontinued since 2002).
Benzalkonium chloride D Dermatologicals. Dermatologicals D08. Antiseptics and disinfectants — Canada OTC —
Benzoyl peroxide D Dermatologicals. Dermatologicals D10. Anti-acne preparations 1981 Canada OTC OTC for preparations of 5% or less as a single ingredient. Rx in concentrations greater than 5% or when sold in combination with another medicinal ingredient.
Selenium sulphide D Dermatologicals. Dermatologicals D01. Antifungals for dermatological use 2003 Canada OTC —
Hyaluronic acid (topical) D Dermatologicals. Dermatologicals D03. Preparations for treatment of wounds and ulcers 1998 Canada OTC —
Nizatidine A Alimentary tract and metabolism. Alimentary tract and metabolism A02. Drugs for acid related disorders 1998 Canada OTC Nizatidine 75mg, for the symptomatic treatment of heartburn and acid indigestion.
Bisacodyl A Alimentary tract and metabolism. Alimentary tract and metabolism A06. Laxatives 2014 Canada OTC OTC in concentrations of 5mg or less per oral dosage unit or 10mg or less per rectal dosage unit/suppository, in package sizes containing no more than 50mg of bisacodyl .
Lactitol A Alimentary tract and metabolism. Alimentary tract and metabolism A06. Laxatives — Canada OTC No product currently marketed.
Lactulose A Alimentary tract and metabolism. Alimentary tract and metabolism A06. Laxatives — Canada OTC 667mg/ml.
Macrogol (Polyethylene glycol 3350) A Alimentary tract and metabolism. Alimentary tract and metabolism A06. Laxatives — Canada OTC Macrogol is OTC in 15% lubricating nasal gel, 15% lubricating nasal mist and 160mg/ml nasal lubricant.
Picosulfate (sodium) A Alimentary tract and metabolism. Alimentary tract and metabolism A06. Laxatives — Canada OTC Ethical OTC status (medicine which does not require a prescription but is generally prescribed by a medical practitioner).
Loperamide A Alimentary tract and metabolism. Alimentary tract and metabolism A07. Antidiarrheals, intestinal antiinflammatory/antiinfective agents 1986 Canada OTC —
Calcium carbonate A Alimentary tract and metabolism. Alimentary tract and metabolism A02. Drugs for acid related disorders — Canada OTC Regulated as a natural health product.
Miconazole (topical) D Dermatologicals. Dermatologicals D01. Antifungals for dermatological use 1994 Canada OTC —
Vitamin A (Retinol) A Alimentary tract and metabolism. Alimentary tract and metabolism A11. Vitamins — Canada OTC Vitamin A is regulated as a natural health product, except in oral dosage forms containing more than 10,000 IU of Vitamin A, where the largest recommended daily dosage shown on the label would, if consumed by a person, result in the daily intake by that person of more than 10,000 IU of Vitamin A.
Selenium A Alimentary tract and metabolism. Alimentary tract and metabolism A12. Mineral supplements 2003 Canada OTC Regulated as a natural health product.
Ketoconazole (topical) D Dermatologicals. Dermatologicals D01. Antifungals for dermatological use 1994 Canada OTC —
Adenosine C Cardiovascular system. Cardiovascular system C01. Cardiac therapy 2013 Canada OTC Unless sold or recommended for administration by IV injection, Adenoside-containing products are regulated as natural health products.
Nitro-glycerine C Cardiovascular system. Cardiovascular system C01. Cardiac therapy — Canada OTC Ethical OTC status (medicine which does not require a prescription but is generally prescribed by a medical practitioner).
Hyoscine butylbromide A Alimentary tract and metabolism. Alimentary tract and metabolism A03. Drugs for functional gastrointestinal disorders 2016 Canada OTC Injectable hyoscine butylbromide has been reverse-switched to prescription status from ethical OTC status (medicine which does not require a prescription but is generally prescribed by a medical practitioner). Oral hyoscine butylbromide remains ethical OTC status.
Lovastatin C Cardiovascular system. Cardiovascular system C10. Lipid modifying agents 2014 Canada OTC Maximum daily dose 1mg.
Dicyclomine (Dicycloverine) A Alimentary tract and metabolism. Alimentary tract and metabolism A03. Drugs for functional gastrointestinal disorders 1998 Canada OTC Ethical OTC status (medicine which does not require a prescription but is generally prescribed by a medical practitioner).
Nystatin D Dermatologicals. Dermatologicals D01. Antifungals for dermatological use 1998 Canada OTC For topical use on the skin.
Tioconazole D Dermatologicals. Dermatologicals D01. Antifungals for dermatological use 1995 Canada OTC No OTC product currently marketed (discontinued since 2002).
Butenafine D Dermatologicals. Dermatologicals D01. Antifungals for dermatological use 1999 Canada OTC 1% cream.
Ranitidine A Alimentary tract and metabolism. Alimentary tract and metabolism A02. Drugs for acid related disorders 1997 Canada OTC 75mg or less per dosage unit, for symptomatic treatment of heartburn and acid indigestion. 150mg dosage switched in 2007.
Clotrimazole (topical) D Dermatologicals. Dermatologicals D01. Antifungals for dermatological use 1994 Canada OTC General sale.
Dimenhydrinate (diphenhydramine and 8-chlorotheophylline) A Alimentary tract and metabolism. Alimentary tract and metabolism A04. Antiemetics and antinauseants 1999 Canada OTC —
Hyoscine (Scopolamine) A Alimentary tract and metabolism. Alimentary tract and metabolism A04. Antiemetics and antinauseants 2016 Canada OTC Ethical OTC status (medicine which does not require a prescription but is generally prescribed by a medical practitioner).
Cimetidine A Alimentary tract and metabolism. Alimentary tract and metabolism A02. Drugs for acid related disorders 1997 Canada OTC When sold in concentrations of 200 mg or less per oral dosage unit and indicated for the treatment of heartburn. 100mg switched in 1997, 200mg switched in 2000.
Fluconazole D Dermatologicals. Dermatologicals D01. Antifungals for dermatological use 2010 Canada OTC Non-prescription status for 150mg of fluconazole for oral use in the treatment of vaginal candidiasis.
Glucosamine M Musculo-skeletal system. Musculo-skeletal system M01. Antiinflammatory and antirheumatic products — Canada OTC Regulated as a natural health product.
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