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Ingredient | ATC Level 1 | ATC Level 2 | Year Of Switch | Country | Status | Additional Information |
---|---|---|---|---|---|---|
Triamcinolone | D Dermatologicals. Dermatologicals | D07. Corticosteroids, dermatological preparations | — | Japan | OTC | Rx under ATC code D07. OTC under ATC code A01 since 2006 for the treatment of stomatitis. |
Clotrimazole (vaginal) | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G01. Gynecological antiinfectives and antiseptics | 2011 | Japan | OTC | Vaginal tablet. Daily dose 100mg. 1% cream for external use of vulvar candidiasis, to be used 2-3 times a day in conjunction with vaginal tablets. |
Tolnaftate | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | — | Japan | OTC | Ointment, cream, liquid formulation. 2%, apply once or twice a day. |
Prednisolone | D Dermatologicals. Dermatologicals | D07. Corticosteroids, dermatological preparations | 1992 | Japan | OTC | Ointment, cream formulations. 0.15% of Prednisolone valerate acetate ester in a preparation. Apply several times a day. |
Benzalkonium chloride | D Dermatologicals. Dermatologicals | D08. Antiseptics and disinfectants | — | Japan | OTC | — |
Minoxidil (topical) | D Dermatologicals. Dermatologicals | D11. Other dermatological preparations | 1999 | Japan | OTC | Immediate OTC sale in 1999 (no switch from Rx). 1% liquid formulation for men since 1999. Also 1% for women since 2005. Maximum strength 5% for men since 2009. |
Oxiconazole | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1993 | Japan | OTC | Liquid and gel formulations. 1% in a preparation. Apply once a day. |
Tioconazole | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1991 | Japan | OTC | — |
Chlortetracycline (topical) | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | Japan | OTC | 0.5% ointment. Apply several times a day. |
Hydrocortisone (topical) | D Dermatologicals. Dermatologicals | D07. Corticosteroids, dermatological preparations | 1990 | Japan | OTC | Ointment, cream formulations. 0.05% of Hydrocortisone butyl ester in a preparation. Apply several times a day. |
Sulconazole nitrate (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1993 | Japan | OTC | — |
Dexchlorpheniramine | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | — | Japan | OTC | — |
Hyoscine butylbromide | A Alimentary tract and metabolism. Alimentary tract and metabolism | A03. Drugs for functional gastrointestinal disorders | 1987 | Japan | OTC | Tablets, capsules. 10mg per dose up to three times a day as Butylscopolamine bromide for adults and adolescents 15 years of age and over. |
Povidone iodine | D Dermatologicals. Dermatologicals | D08. Antiseptics and disinfectants | — | Japan | OTC | — |
Diphenylpyraline | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | — | Japan | OTC | — |
Econazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1988 | Japan | OTC | Liquid, ointment, cream or spray formulations. 1% in a preparation. Apply 1-3 times a day. |
Isoconazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2008 | Japan | OTC | Cream formulation. 1% in a preparation. Apply 2-3 times a day. |
Terbinafine | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2002 | Japan | OTC | Cream, liquid formulation. 1%, once a day. |
Nystatin | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | — | Japan | OTC | Topical combination drug with chloramphenicol and fradiomycin sulphate. Ointment formulation. 100,000 unit/g in a preparation. Apply several times a day. |
Aciclovir (topical) | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | 2007 | Japan | OTC | Switched in 2007 for recurrent herpes mouth ulcers. Distribution restricted to pharmacies following an initial doctor consultation. 5% cream, ointment formulations. Apply 3-5 times a day. |
Lysozyme HCl | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | Japan | OTC | Registration on oral preparations was revoked. Now available as topical combination drugs such as hemorrhoidal preparation. |
Tetracycline | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | — | Japan | OTC | Combination of oxytetracycline hydrochloride and hydrocortisone acetate for topical use. Combination of oxytetracycline hydrochloride and polymyxin B for topical use. |
Fluoride (sodium) | A Alimentary tract and metabolism. Alimentary tract and metabolism | A01. Stomatological preparations | 2015 | Japan | OTC | Mouthwash preparation. Daily dose 5-10mg in children over 4 years. |
Bisacodyl | A Alimentary tract and metabolism. Alimentary tract and metabolism | A06. Laxatives | — | Japan | OTC | — |
Sucralfate | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | 1981 | Japan | OTC | Switched as a GI combination drug. Tablets, granules, powder, liquid formulation. 500mg a dose up to three times a day for adults and adolescents 15 years of age and older. |
Dicyclomine (Dicycloverine) | A Alimentary tract and metabolism. Alimentary tract and metabolism | A03. Drugs for functional gastrointestinal disorders | — | Japan | OTC | — |
Dimeticone | A Alimentary tract and metabolism. Alimentary tract and metabolism | A03. Drugs for functional gastrointestinal disorders | — | Japan | OTC | — |
Aluminium hydroxide | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | — | Japan | OTC | — |
Calcium carbonate | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | — | Japan | OTC | — |
Dimenhydrinate (diphenhydramine and 8-chlorotheophylline) | A Alimentary tract and metabolism. Alimentary tract and metabolism | A04. Antiemetics and antinauseants | — | Japan | OTC | — |
Hyoscine (Scopolamine) | A Alimentary tract and metabolism. Alimentary tract and metabolism | A04. Antiemetics and antinauseants | — | Japan | OTC | — |
Picosulfate (sodium) | A Alimentary tract and metabolism. Alimentary tract and metabolism | A06. Laxatives | 1983 | Japan | OTC | Tablet formulation. Maximum dose 7.5mg per day as sodium picosulfate hydrate for adults and adolescents 15 years of age and over. For children between 11 and 14, maximum dose 4.5mg per day. |
Loperamide | A Alimentary tract and metabolism. Alimentary tract and metabolism | A07. Antidiarrheals, intestinal antiinflammatory/antiinfective agents | 1989 | Japan | OTC | Capsule, tablet, film formulations. 0.5mg a dose, up to twice a day for adults and adolescents 15 years of age and over. |
Cetraxate | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | 1987 | Japan | OTC | Switched as a GI combination drug. Tablet, granule formulations. 200mg a dose, three times a day for adults and adolescents 15 years of age and over. |
Cimetidine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | 1997 | Japan | OTC | Tablets, micro granules. 100mg per dose up to three times a day for adults and adolescents 15 years of age and over. |
Vitamin A (Retinol) | A Alimentary tract and metabolism. Alimentary tract and metabolism | A11. Vitamins | — | Japan | OTC | — |
Famotidine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | 1997 | Japan | OTC | Tablets, powder, liquid formulation. 10mg per dose up to twice a day for adults and adolescents 15 years of age and over. |
Tranexamic acid | B Blood and blood forming organs. Blood and blood forming organs | B02. Antihemorrhagics | — | Japan | OTC | Tablet, liquid formulations. For cough and cold, maximum 750mg or 280mg per day, respectively three times or up to four times a day. Additional indications for chloasma in 2007. (ATC code D11) |
Adenosine | C Cardiovascular system. Cardiovascular system | C01. Cardiac therapy | — | Japan | OTC | Adenosine triphosphate disodium hydrate. Tablet formulation. As a combination drug with B-complex vitamins, 20mg a dose, three times a day for adults and adolescents 15 years of age and over. |
Miconazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1987 | Japan | OTC | Cream, liquid formulation. 1%, once a day. |
Ubidecarenone | C Cardiovascular system. Cardiovascular system | C01. Cardiac therapy | 1990 | Japan | OTC | Tablets. 30mg per dose up to three times a day for adults and adolescents 15 years of age and over. |
Nizatidine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | 2005 | Japan | OTC | Tablets, capsules, liquid formulation. 75mg a dose up to twice a day for adults and adolescents 15 years of age and over. |
Neticonazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2002 | Japan | OTC | OTC under ATC code D01 and G01. |
Amorolfine (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2002 | Japan | OTC | Cream, liquid formulation. 0.5%. Apply once a day. |
Bifonazole | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1993 | Japan | OTC | Topical liquid formulation, cream, gel or spray. 1% in a preparation. Apply once a day. |
Butenafine | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2002 | Japan | OTC | Topical liquid formulation, cream, gel, spray or powder-form spray. 1% in a preparation. Apply once a day. |
Ciclopirox Olamine | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1987 | Japan | OTC | Topical liquid formulation, cream. 1%, apply 2-3 times a day. |
Clotrimazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1980 | Japan | OTC | Liquid, ointment, cream, gel or powder-form spray formulations. 1% in a preparation. Apply 2-3 times a day. |
Ranitidine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | 1997 | Japan | OTC | Tablets. 63mg per dose up to twice a day for adults and adolescents 15 years of age and over. Discontinued. |
Miconazole (vaginal) | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G01. Gynecological antiinfectives and antiseptics | 2008 | Japan | OTC | Vaginal tablet. Daily dose 100mg. 1% cream for exrternal use of vulvar candidiasis, 2-3 times a day. |
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