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Ingredient ATC Level 1 ATC Level 2 Year Of Switch Country Status Additional Information
Benzoyl peroxide D Dermatologicals. Dermatologicals D10. Anti-acne preparations 1981 Canada OTC OTC for preparations of 5% or less as a single ingredient. Rx in concentrations greater than 5% or when sold in combination with another medicinal ingredient.
Loperamide A Alimentary tract and metabolism. Alimentary tract and metabolism A07. Antidiarrheals, intestinal antiinflammatory/antiinfective agents 1986 Canada OTC
Hydrocortisone (topical) D Dermatologicals. Dermatologicals D07. Corticosteroids, dermatological preparations 1986 Canada OTC 0.5% topical switched in 1986, 1% topical switched in 2014.
Loratadine R Respiratory system. Respiratory system R06. Antihistamines for systemic use 1988 Canada OTC On 22 September 2002, the Nonprescription Drug Scheduling Advisory Committee recommended that loratadine and its salts and preparations in products marketed for adult use (age 12 years and over) be unscheduled (i.e. available on general sale). Loratadine marketed for paediatric use (under 12 years) will remain Schedule 3 (available without a prescription, these drugs are to be sold from the self-selection area of the pharmacy which is operated under the direct supervision of the pharmacist).
Ibuprofen (topical) M Musculo-skeletal system. Musculo-skeletal system M02. Topical products for joint and muscular pain 1989 Canada OTC
Ibuprofen (oral) M Musculo-skeletal system. Musculo-skeletal system M01. Antiinflammatory and antirheumatic products 1989 Canada OTC Ibuprofen combinations were switched in 1994. As from August 2016, Ibuprofen is available without a prescription in the following cases: a) An oral dosage form that provides 400mg or less per dosage unit; or b) A modified-release oral dosage form that provides 600mg or less per dosage unit.
Nicotine (gum) N Nervous system. Nervous system N07. Other nervous system drugs 1992 Canada OTC Both 2mg and 4mg strength (the latter switched in 1997).
Miconazole (vaginal) G Genito urinary system and sex hormones. Genito urinary system and sex hormones G01. Gynecological antiinfectives and antiseptics 1994 Canada OTC
Clotrimazole (topical) D Dermatologicals. Dermatologicals D01. Antifungals for dermatological use 1994 Canada OTC General sale.
Clotrimazole (vaginal) G Genito urinary system and sex hormones. Genito urinary system and sex hormones G01. Gynecological antiinfectives and antiseptics 1994 Canada OTC Schedule 3 (available without prescription but to be sold from the self-selection area of the pharmacy which is operated under the direct supervision of the pharmacist) for human use in preparations for intra-vaginal use.
Ketoconazole (topical) D Dermatologicals. Dermatologicals D01. Antifungals for dermatological use 1994 Canada OTC
Miconazole (topical) D Dermatologicals. Dermatologicals D01. Antifungals for dermatological use 1994 Canada OTC
Cetirizine R Respiratory system. Respiratory system R06. Antihistamines for systemic use 1995 Canada OTC General sale in concentrations of 10mg equivalent to 8.5mg or less of cetrizine base per dosage unit in products marketed for adult use (age 12 and over). Schedule 3 (available without a prescription but to be sold from the self-selection area of the pharmacy which is operated under the direct supervision of the pharmacist) in concentrations of 10mg equivalent to 8.5mg or less of cetirizine base per dosage unit, in products marketed for paediatric use (under 12 years of age).
Tioconazole D Dermatologicals. Dermatologicals D01. Antifungals for dermatological use 1995 Canada OTC No OTC product currently marketed (discontinued since 2002).
Famotidine A Alimentary tract and metabolism. Alimentary tract and metabolism A02. Drugs for acid related disorders 1996 Canada OTC For the treatment & prevention of acid-related gastrointestinal symptoms in adults and children over 12 years of age. Dosage is 10mg per tablet, Maximum Daily Dose is 20mg (treatment should not exceed two weeks). 20 & 40mg dosages switched in 2007.
Cimetidine A Alimentary tract and metabolism. Alimentary tract and metabolism A02. Drugs for acid related disorders 1997 Canada OTC When sold in concentrations of 200 mg or less per oral dosage unit and indicated for the treatment of heartburn. 100mg switched in 1997, 200mg switched in 2000.
Ranitidine A Alimentary tract and metabolism. Alimentary tract and metabolism A02. Drugs for acid related disorders 1997 Canada OTC 75mg or less per dosage unit, for symptomatic treatment of heartburn and acid indigestion. 150mg dosage switched in 2007.
Chlorpheniramine (Chlorphenamine) R Respiratory system. Respiratory system R06. Antihistamines for systemic use 1997 Canada OTC General sale.
Oxiconazole D Dermatologicals. Dermatologicals D01. Antifungals for dermatological use 1997 Canada OTC Switched directly to OTC status in 1997, but no product currently marketed (discontinued since 2002).
Dyclonine (oral) N Nervous system. Nervous system N01. Anesthetics 1998 Canada OTC Not registered or not marketed under this ATC code. OTC under ATC code R02.
Orphenadrine M Musculo-skeletal system. Musculo-skeletal system M03. Muscle relaxants 1998 Canada OTC
Pyrantel P Antiparasitic products, insecticides and repellents. Antiparasitic products, insecticides and repellents P02. Anthelmintics 1998 Canada OTC Pyrantel pamoate.
Fluoride (sodium) A Alimentary tract and metabolism. Alimentary tract and metabolism A01. Stomatological preparations 1998 Canada OTC Regulated as a natural health product.
Cromoglicic acid R Respiratory system. Respiratory system R01. Nasal preparations 1998 Canada OTC Sodium cromoglycate, 2% nasal solution and 2% ophthalmic solution, for the prevention and relief of seasonal allergy symptoms (this dosage form is antihistamine).
Prilocaine N Nervous system. Nervous system N01. Anesthetics 1998 Canada OTC
Naphazoline R Respiratory system. Respiratory system R01. Nasal preparations 1998 Canada OTC
Nizatidine A Alimentary tract and metabolism. Alimentary tract and metabolism A02. Drugs for acid related disorders 1998 Canada OTC Nizatidine 75mg, for the symptomatic treatment of heartburn and acid indigestion.
Methocarbamol M Musculo-skeletal system. Musculo-skeletal system M03. Muscle relaxants 1998 Canada OTC
Benzocaine N Nervous system. Nervous system N01. Anesthetics 1998 Canada OTC General sale for topical applications on the skin. Schedule 2 (prescription not required but the medicine is available only from the pharmacist, no public access, no self-selection) for parenteral or ophthalmic use. Schedule 3 (available without a prescription but to be sold from the self-selection area of the pharmacy which is operated under the direct supervision of the pharmacist) for topical use on mucous membranes for teething.
Oxymetazoline R Respiratory system. Respiratory system R01. Nasal preparations 1998 Canada OTC In nasal preparations for adult use and in ophthalmic products.
Xylometazoline (nasal) R Respiratory system. Respiratory system R01. Nasal preparations 1998 Canada OTC
Dexbrompheniramine R Respiratory system. Respiratory system R06. Antihistamines for systemic use 1998 Canada OTC Not registered or not marketed under this ATC code. OTC under ATC code R01.
Tetrahydrozoline R Respiratory system. Respiratory system R01. Nasal preparations 1998 Canada OTC
Diphenhydramine R Respiratory system. Respiratory system R06. Antihistamines for systemic use 1998 Canada OTC
Carbinoxamine R Respiratory system. Respiratory system R06. Antihistamines for systemic use 1998 Canada OTC Schedule 3 (available without a prescription but to be sold from the self-selection area of the pharmacy which is operated under the direct supervision of the pharmacist).
Bufexamac (topical) M Musculo-skeletal system. Musculo-skeletal system M01. Antiinflammatory and antirheumatic products 1998 Canada OTC Schedule 2 (a prescription is not required but the medicine is only available from the pharmacist, no public access and no self-selection).
Cyproheptadine R Respiratory system. Respiratory system R06. Antihistamines for systemic use 1998 Canada OTC
Diphenylpyraline R Respiratory system. Respiratory system R06. Antihistamines for systemic use 1998 Canada OTC Not registered or not marketed under this ATC code. OTC under ATC code R05.
Acetylcysteine R Respiratory system. Respiratory system R05. Cough and cold preparations 1998 Canada OTC
Hyaluronic acid (topical) D Dermatologicals. Dermatologicals D03. Preparations for treatment of wounds and ulcers 1998 Canada OTC
Nicotine (patch) N Nervous system. Nervous system N07. Other nervous system drugs 1998 Canada OTC 22mg/day and less, as an aid in smoking cessation.
Clemastine R Respiratory system. Respiratory system R06. Antihistamines for systemic use 1998 Canada OTC Schedule 3 (available without a prescription but to be sold from the self-selection area of the pharmacy which is operated under the direct supervision of the pharmacist).
Dicyclomine (Dicycloverine) A Alimentary tract and metabolism. Alimentary tract and metabolism A03. Drugs for functional gastrointestinal disorders 1998 Canada OTC Ethical OTC status (medicine which does not require a prescription but is generally prescribed by a medical practitioner).
Nystatin D Dermatologicals. Dermatologicals D01. Antifungals for dermatological use 1998 Canada OTC For topical use on the skin.
Phenylephrine R Respiratory system. Respiratory system R01. Nasal preparations 1998 Canada OTC
Methenamine J Antiinfectives for systemic use. Antiinfectives for systemic use J01. Antibacterials for systemic use 1998 Canada OTC Ethical OTC status (medicine which does not require a prescription but is generally prescribed by a medical practitioner).
Bacitracin (topical) R Respiratory system. Respiratory system R02. Throat preparations 1998 Canada OTC General sale for topical use. Schedule 3 (available without a prescription but to be sold from the self-selection area of the pharmacy which is operated under the direct supervision of the pharmacist) for ophthalmic use.
Dexchlorpheniramine R Respiratory system. Respiratory system R06. Antihistamines for systemic use 1998 Canada OTC No product currently marketed.
Chlorzoxazone M Musculo-skeletal system. Musculo-skeletal system M03. Muscle relaxants 1998 Canada OTC Schedule 3 (available without prescription but to be sold from the self-selection area of the pharmacy which is operated under the direct supervision of the pharmacis).
Doxylamine succinate R Respiratory system. Respiratory system R06. Antihistamines for systemic use 1998 Canada OTC New uses in 2013 for nausea during pregnancy.
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