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Ingredient | ATC Level 1 | ATC Level 2 | Year Of Switch | Country | Status | Additional Information |
---|---|---|---|---|---|---|
Benzoyl peroxide | D Dermatologicals. Dermatologicals | D10. Anti-acne preparations | 1981 | Canada | OTC | OTC for preparations of 5% or less as a single ingredient. Rx in concentrations greater than 5% or when sold in combination with another medicinal ingredient. |
Loperamide | A Alimentary tract and metabolism. Alimentary tract and metabolism | A07. Antidiarrheals, intestinal antiinflammatory/antiinfective agents | 1986 | Canada | OTC | — |
Hydrocortisone (topical) | D Dermatologicals. Dermatologicals | D07. Corticosteroids, dermatological preparations | 1986 | Canada | OTC | 0.5% topical switched in 1986, 1% topical switched in 2014. |
Loratadine | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | 1988 | Canada | OTC | On 22 September 2002, the Nonprescription Drug Scheduling Advisory Committee recommended that loratadine and its salts and preparations in products marketed for adult use (age 12 years and over) be unscheduled (i.e. available on general sale). Loratadine marketed for paediatric use (under 12 years) will remain Schedule 3 (available without a prescription, these drugs are to be sold from the self-selection area of the pharmacy which is operated under the direct supervision of the pharmacist). |
Ibuprofen (topical) | M Musculo-skeletal system. Musculo-skeletal system | M02. Topical products for joint and muscular pain | 1989 | Canada | OTC | — |
Ibuprofen (oral) | M Musculo-skeletal system. Musculo-skeletal system | M01. Antiinflammatory and antirheumatic products | 1989 | Canada | OTC | Ibuprofen combinations were switched in 1994. As from August 2016, Ibuprofen is available without a prescription in the following cases: a) An oral dosage form that provides 400mg or less per dosage unit; or b) A modified-release oral dosage form that provides 600mg or less per dosage unit. |
Nicotine (gum) | N Nervous system. Nervous system | N07. Other nervous system drugs | 1992 | Canada | OTC | Both 2mg and 4mg strength (the latter switched in 1997). |
Miconazole (vaginal) | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G01. Gynecological antiinfectives and antiseptics | 1994 | Canada | OTC | — |
Clotrimazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1994 | Canada | OTC | General sale. |
Clotrimazole (vaginal) | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G01. Gynecological antiinfectives and antiseptics | 1994 | Canada | OTC | Schedule 3 (available without prescription but to be sold from the self-selection area of the pharmacy which is operated under the direct supervision of the pharmacist) for human use in preparations for intra-vaginal use. |
Ketoconazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1994 | Canada | OTC | — |
Miconazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1994 | Canada | OTC | — |
Cetirizine | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | 1995 | Canada | OTC | General sale in concentrations of 10mg equivalent to 8.5mg or less of cetrizine base per dosage unit in products marketed for adult use (age 12 and over). Schedule 3 (available without a prescription but to be sold from the self-selection area of the pharmacy which is operated under the direct supervision of the pharmacist) in concentrations of 10mg equivalent to 8.5mg or less of cetirizine base per dosage unit, in products marketed for paediatric use (under 12 years of age). |
Tioconazole | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1995 | Canada | OTC | No OTC product currently marketed (discontinued since 2002). |
Famotidine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | 1996 | Canada | OTC | For the treatment & prevention of acid-related gastrointestinal symptoms in adults and children over 12 years of age. Dosage is 10mg per tablet, Maximum Daily Dose is 20mg (treatment should not exceed two weeks). 20 & 40mg dosages switched in 2007. |
Cimetidine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | 1997 | Canada | OTC | When sold in concentrations of 200 mg or less per oral dosage unit and indicated for the treatment of heartburn. 100mg switched in 1997, 200mg switched in 2000. |
Ranitidine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | 1997 | Canada | OTC | 75mg or less per dosage unit, for symptomatic treatment of heartburn and acid indigestion. 150mg dosage switched in 2007. |
Chlorpheniramine (Chlorphenamine) | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | 1997 | Canada | OTC | General sale. |
Oxiconazole | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1997 | Canada | OTC | Switched directly to OTC status in 1997, but no product currently marketed (discontinued since 2002). |
Dyclonine (oral) | N Nervous system. Nervous system | N01. Anesthetics | 1998 | Canada | OTC | Not registered or not marketed under this ATC code. OTC under ATC code R02. |
Orphenadrine | M Musculo-skeletal system. Musculo-skeletal system | M03. Muscle relaxants | 1998 | Canada | OTC | — |
Pyrantel | P Antiparasitic products, insecticides and repellents. Antiparasitic products, insecticides and repellents | P02. Anthelmintics | 1998 | Canada | OTC | Pyrantel pamoate. |
Fluoride (sodium) | A Alimentary tract and metabolism. Alimentary tract and metabolism | A01. Stomatological preparations | 1998 | Canada | OTC | Regulated as a natural health product. |
Cromoglicic acid | R Respiratory system. Respiratory system | R01. Nasal preparations | 1998 | Canada | OTC | Sodium cromoglycate, 2% nasal solution and 2% ophthalmic solution, for the prevention and relief of seasonal allergy symptoms (this dosage form is antihistamine). |
Prilocaine | N Nervous system. Nervous system | N01. Anesthetics | 1998 | Canada | OTC | — |
Naphazoline | R Respiratory system. Respiratory system | R01. Nasal preparations | 1998 | Canada | OTC | — |
Nizatidine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | 1998 | Canada | OTC | Nizatidine 75mg, for the symptomatic treatment of heartburn and acid indigestion. |
Methocarbamol | M Musculo-skeletal system. Musculo-skeletal system | M03. Muscle relaxants | 1998 | Canada | OTC | — |
Benzocaine | N Nervous system. Nervous system | N01. Anesthetics | 1998 | Canada | OTC | General sale for topical applications on the skin. Schedule 2 (prescription not required but the medicine is available only from the pharmacist, no public access, no self-selection) for parenteral or ophthalmic use. Schedule 3 (available without a prescription but to be sold from the self-selection area of the pharmacy which is operated under the direct supervision of the pharmacist) for topical use on mucous membranes for teething. |
Oxymetazoline | R Respiratory system. Respiratory system | R01. Nasal preparations | 1998 | Canada | OTC | In nasal preparations for adult use and in ophthalmic products. |
Xylometazoline (nasal) | R Respiratory system. Respiratory system | R01. Nasal preparations | 1998 | Canada | OTC | — |
Dexbrompheniramine | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | 1998 | Canada | OTC | Not registered or not marketed under this ATC code. OTC under ATC code R01. |
Tetrahydrozoline | R Respiratory system. Respiratory system | R01. Nasal preparations | 1998 | Canada | OTC | — |
Diphenhydramine | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | 1998 | Canada | OTC | — |
Carbinoxamine | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | 1998 | Canada | OTC | Schedule 3 (available without a prescription but to be sold from the self-selection area of the pharmacy which is operated under the direct supervision of the pharmacist). |
Bufexamac (topical) | M Musculo-skeletal system. Musculo-skeletal system | M01. Antiinflammatory and antirheumatic products | 1998 | Canada | OTC | Schedule 2 (a prescription is not required but the medicine is only available from the pharmacist, no public access and no self-selection). |
Cyproheptadine | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | 1998 | Canada | OTC | — |
Diphenylpyraline | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | 1998 | Canada | OTC | Not registered or not marketed under this ATC code. OTC under ATC code R05. |
Acetylcysteine | R Respiratory system. Respiratory system | R05. Cough and cold preparations | 1998 | Canada | OTC | — |
Hyaluronic acid (topical) | D Dermatologicals. Dermatologicals | D03. Preparations for treatment of wounds and ulcers | 1998 | Canada | OTC | — |
Nicotine (patch) | N Nervous system. Nervous system | N07. Other nervous system drugs | 1998 | Canada | OTC | 22mg/day and less, as an aid in smoking cessation. |
Clemastine | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | 1998 | Canada | OTC | Schedule 3 (available without a prescription but to be sold from the self-selection area of the pharmacy which is operated under the direct supervision of the pharmacist). |
Dicyclomine (Dicycloverine) | A Alimentary tract and metabolism. Alimentary tract and metabolism | A03. Drugs for functional gastrointestinal disorders | 1998 | Canada | OTC | Ethical OTC status (medicine which does not require a prescription but is generally prescribed by a medical practitioner). |
Nystatin | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1998 | Canada | OTC | For topical use on the skin. |
Phenylephrine | R Respiratory system. Respiratory system | R01. Nasal preparations | 1998 | Canada | OTC | — |
Methenamine | J Antiinfectives for systemic use. Antiinfectives for systemic use | J01. Antibacterials for systemic use | 1998 | Canada | OTC | Ethical OTC status (medicine which does not require a prescription but is generally prescribed by a medical practitioner). |
Bacitracin (topical) | R Respiratory system. Respiratory system | R02. Throat preparations | 1998 | Canada | OTC | General sale for topical use. Schedule 3 (available without a prescription but to be sold from the self-selection area of the pharmacy which is operated under the direct supervision of the pharmacist) for ophthalmic use. |
Dexchlorpheniramine | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | 1998 | Canada | OTC | No product currently marketed. |
Chlorzoxazone | M Musculo-skeletal system. Musculo-skeletal system | M03. Muscle relaxants | 1998 | Canada | OTC | Schedule 3 (available without prescription but to be sold from the self-selection area of the pharmacy which is operated under the direct supervision of the pharmacis). |
Doxylamine succinate | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | 1998 | Canada | OTC | New uses in 2013 for nausea during pregnancy. |
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