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| Ingredient | ATC Level 1 | ATC Level 2 | Year Of Switch | Country | Status | Additional Information |
|---|---|---|---|---|---|---|
| Econazole (vaginal) | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G01. Gynecological antiinfectives and antiseptics | 1995 | Singapore | OTC | Econazole vaginal preparations were switched from POM to P in November 1995. |
| Loratadine | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | 1995 | Singapore | OTC | — |
| Isoconazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1995 | Singapore | OTC | Isoconazole vaginal preparations were switched from POM to P in November 1995. |
| Tioconazole | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 1995 | Singapore | OTC | Tioconazole vaginal preparations were switched from POM to P in November 1995. |
| Clotrimazole (vaginal) | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G01. Gynecological antiinfectives and antiseptics | 1995 | Singapore | OTC | Clotrimazole vaginal preparations were switched from POM to P in November 1995. |
| Cromoglicic acid | R Respiratory system. Respiratory system | R01. Nasal preparations | 1995 | Singapore | OTC | Sodium cromoglycate 2% nasal spray for the treatment of allergic rhinitis. |
| Miconazole (vaginal) | G Genito urinary system and sex hormones. Genito urinary system and sex hormones | G01. Gynecological antiinfectives and antiseptics | 1995 | Singapore | OTC | Miconazole vaginal preparations were switched from POM to P in November 1995. |
| Cimetidine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | 1995 | Singapore | OTC | Cimetidine oral preparations for a) short-term relief of heartburn, dyspepsia and hyperacidity, and b) prophylactic management of nocturnal heartburn. Maximum daily dose of a) 200mg and b) 100mg (as a single night-time dose), maximum supply of 2 weeks. |
| Cetirizine | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | 1997 | Singapore | OTC | — |
| Tyrothricin | R Respiratory system. Respiratory system | R02. Throat preparations | 1997 | Singapore | OTC | — |
| Acrivastine | R Respiratory system. Respiratory system | R06. Antihistamines for systemic use | 1997 | Singapore | OTC | — |
| Ibuprofen (topical) | M Musculo-skeletal system. Musculo-skeletal system | M02. Topical products for joint and muscular pain | 1998 | Singapore | OTC | — |
| Diclofenac (topical) | M Musculo-skeletal system. Musculo-skeletal system | M02. Topical products for joint and muscular pain | 1998 | Singapore | OTC | Diclofenac topical preparations switched to pharmacy sale in 1998. Topical preparations 1% switched to general sale in October 2002. |
| Ketoprofen (topical) | M Musculo-skeletal system. Musculo-skeletal system | M02. Topical products for joint and muscular pain | 1998 | Singapore | OTC | — |
| Nicotine (patch) | N Nervous system. Nervous system | N07. Other nervous system drugs | 1999 | Singapore | OTC | — |
| Piroxicam (topical) | M Musculo-skeletal system. Musculo-skeletal system | M02. Topical products for joint and muscular pain | 2000 | Singapore | OTC | Piroxicam dermatological preparations were switched from POM to P in January 2000. |
| Beclometasone (nasal) | R Respiratory system. Respiratory system | R01. Nasal preparations | 2000 | Singapore | OTC | Beclomethasone nasal spray for prevention and treatment of allergic rhinitis for persons at least 18 years of age at a maximum daily dose of 200 micrograms/nostril and a maximum of 3 months' supply. |
| Clotrimazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2000 | Singapore | OTC | Clotrimazole dermatological preparations 1% were switched from P to GSL in September 2000. |
| Famotidine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | 2000 | Singapore | OTC | Famotidine oral preparations for short-term relief of heartburn, dyspepsia and hyperacidity at a maximum daily dose of 300mg and a maximum of 2 weeks' supply. |
| Budesonide (nasal) | R Respiratory system. Respiratory system | R01. Nasal preparations | 2000 | Singapore | OTC | Budesonide nasal spray for prevention and treatment of allergic rhinitis for persons at least 18 years of age. Pharmacy-only medicine. |
| Domperidone | A Alimentary tract and metabolism. Alimentary tract and metabolism | A03. Drugs for functional gastrointestinal disorders | 2000 | Singapore | OTC | Domperidone oral preparations for relief of postprandial symptoms of excessive fullness, nausea, epigastric bloating and belching, occasionally accompanied by epigastric discomfort and heartburn at a maximum dose of 10mg and a maximum daily dose of 40mg. |
| Nitro-glycerine | C Cardiovascular system. Cardiovascular system | C01. Cardiac therapy | 2000 | Singapore | OTC | Glyceryl trinitrate transdermal preparations. |
| Selenium sulphide | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2000 | Singapore | OTC | Selenium sulfide scalp preparations not exceeding 2.5% were switched from P to GSL in September 2000. |
| Ranitidine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | 2000 | Singapore | OTC | Ranitidine oral preparations for short-term relief of heartburn, dyspepsia and hyperacidity at a maximum daily dose of 300mg and a maximum of 2 weeks' supply. |
| Pyrantel | P Antiparasitic products, insecticides and repellents. Antiparasitic products, insecticides and repellents | P02. Anthelmintics | 2000 | Singapore | OTC | Pyrantel pamoate/embonate. Switched from P to GSL in September 2000. |
| Aciclovir (topical) | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | 2000 | Singapore | OTC | Aciclovir topical for the treatment of cold sores. Maximum strength: 5%, maximum pack size: 2g. |
| Miconazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2000 | Singapore | OTC | Miconazole dermatological preparations 2% were switched from P to GSL in September 2000. |
| Terbinafine | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2000 | Singapore | OTC | Terbinafine 1% dermatological preparations are OTC. |
| Econazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2000 | Singapore | OTC | Econazole dermatological preparations 1% were switched from P to GSL in September 2000. |
| Nicotine (gum) | N Nervous system. Nervous system | N07. Other nervous system drugs | 2002 | Singapore | OTC | Nicotine oral (lozenges/gum) was proposed for declassification from Rx to OTC in 2002. |
| Bromhexine | R Respiratory system. Respiratory system | R05. Cough and cold preparations | 2002 | Singapore | OTC | Bromhexine HCl 8mg tablets and 4mg/5ml liquid switched from POM to P status in November 2002. Bromhexine HCl plus pholcodine as well as Bromhexine HCl liquid 12mg/15ml reclassified from POM to P status with effect from 6 October 2004. |
| Ambroxol | R Respiratory system. Respiratory system | R05. Cough and cold preparations | 2002 | Singapore | OTC | Ambroxol 4mg/5ml elixir and 30mg tablets switched to OTC status in November 2002. Ambroxol lozenges reclassified from Prescription Only Medicine (POM) to Pharmacy only medicine (P) status, with effect from 20 July 2005. |
| Nicotine (oral inhaler) | N Nervous system. Nervous system | N07. Other nervous system drugs | 2002 | Singapore | OTC | Nicotine inhaler 10mg switched from prescription-only to pharmacy-only in August 2002. |
| Nicotine (sublingual) | N Nervous system. Nervous system | N07. Other nervous system drugs | 2002 | Singapore | OTC | Nicotine lozenges and gums were approved as 'Pharmacy' medicines in July 2003 and January 2004, respectively. |
| Ibuprofen (oral) | M Musculo-skeletal system. Musculo-skeletal system | M01. Antiinflammatory and antirheumatic products | 2002 | Singapore | OTC | Ibuprofen oral tablets/caplets 200mg and 100mg/5ml suspension became available for pharmacy only sale in restricted pack sizes from 15 April 2002 for the relief of headache, menstrual pain, backache, muscular and arthritic pain, toothache, and the aches of cold and flu as well as for the reduction of fever. In children: for the reduction of fever, includ-ing post-immunisation pyrexia, and the relief of mild to moderate pain such as sore throat, teething pain and toothache, earache, minor aches and sprains. It is indicated for use in infants from 2 to 6 months old for post-immunisation pyrexia only. |
| Mupirocin (topical) | D Dermatologicals. Dermatologicals | D06. Antibiotics and chemotherapeutics for dermatological use | 2002 | Singapore | OTC | Mupirocin was proposed for declassification from Rx to OTC in 2002. |
| Clobetasone butyrate (topical) | D Dermatologicals. Dermatologicals | D07. Corticosteroids, dermatological preparations | 2002 | Singapore | OTC | Clobetasone butyrate 0.05% was proposed for declassification from Rx to OTC in 2002. |
| Minoxidil (topical) | D Dermatologicals. Dermatologicals | D11. Other dermatological preparations | 2002 | Singapore | OTC | Minoxidil topical. Maximum strength = 5%. |
| Ketoconazole (topical) | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2002 | Singapore | OTC | Ketoconazole topical preparations POM to P Sep 1997; 1% were switched from P to GSL in April 2002. |
| Naproxen | M Musculo-skeletal system. Musculo-skeletal system | M01. Antiinflammatory and antirheumatic products | 2003 | Singapore | OTC | Naproxen sodium tablets 220mg became available OTC in September 2003. |
| Tolnaftate | D Dermatologicals. Dermatologicals | D01. Antifungals for dermatological use | 2003 | Singapore | OTC | Tolnaftate solutions, creams 1% were switched from P to GSL in 2003. |
| Orlistat | A Alimentary tract and metabolism. Alimentary tract and metabolism | A08. Antiobesity preparations | 2005 | Singapore | OTC | Orlistat 120mg capsules reclassified from Prescription Only Medicine (POM) to Pharmacy Only Medicine (P) status with effect from 31 January 2005 to treat people who are obese (BMI of 30 or above). |
| Lactitol | A Alimentary tract and metabolism. Alimentary tract and metabolism | A06. Laxatives | — | Singapore | N.R. | Not registered or not marketed. |
| Bisacodyl | A Alimentary tract and metabolism. Alimentary tract and metabolism | A06. Laxatives | — | Singapore | OTC | — |
| Omeprazole | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | — | Singapore | Rx | — |
| Hymecromone | A Alimentary tract and metabolism. Alimentary tract and metabolism | A05. Bile and liver therapy | — | Singapore | N.R. | Not registered or not marketed. |
| Hyoscine (Scopolamine) | A Alimentary tract and metabolism. Alimentary tract and metabolism | A04. Antiemetics and antinauseants | — | Singapore | OTC | — |
| Nizatidine | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | — | Singapore | Rx | — |
| Carbenoxolone | A Alimentary tract and metabolism. Alimentary tract and metabolism | A02. Drugs for acid related disorders | — | Singapore | OTC | — |
| Dimenhydrinate (diphenhydramine and 8-chlorotheophylline) | A Alimentary tract and metabolism. Alimentary tract and metabolism | A04. Antiemetics and antinauseants | — | Singapore | OTC | — |
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